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Adenovirus-delivered PDCD5 counteracts adriamycin resistance of osteosarcoma cells through enhancing apoptosis and inhibiting Pgp

In the present study, we investigated the roles of PDCD5 (programmed cell death 5) in multidrug re-sistance (MDR) of osteosarcoma cells and the possible lurking mechanisms. An adenovirus expression vector of PDCD5 was constructed and transfected into human adriamycin-resistant osteosarcoma cell line...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Zhao, Hui, Peng, Changliang, Ruan, Guorui, Zhou, Junlin, Li, Yihan, Hai, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307499/
https://ncbi.nlm.nih.gov/pubmed/25664052
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