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Mechanisms and Implications of Dual-Acting Methotrexate in Folate-Targeted Nanotherapeutic Delivery

The rational design of a nanoplatform in drug delivery plays a crucial role in determining its targeting specificity and efficacy in vivo. A conventional approach relies on the surface conjugation of a nanometer-sized particle with two functionally distinct types of molecules, one as a targeting lig...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wong, Pamela T., Choi, Seok Ki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307333/
https://ncbi.nlm.nih.gov/pubmed/25590303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16011772
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