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(+/-)-7alpha,8beta-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo(a)-pyrene is an intermediate in the metabolism and binding to DNA of benzo(a)pyrene.

The addition of borate buffer to the aqueous methanol used to elute hydrocarbon-deoxyribonucleoside derivatives from an LH 20 Sephadex column resulted in the separation of the products of reaction with DNA of the stereoisomers, (+/-)7alpha,8beta-dihydroxy-9alpha,10alpha-epoxy- and (+/-)-7alpha,8beta...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: King, H W, Osborne, M R, Beland, F A, Harvey, R G, Brookes, P
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1976
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1066679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.8.2679
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