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Detection of different types of damage in alkylated DNA by means of human corrective endonuclease (correndonuclease).
Corrective endonuclease (correndunclease) activity of HeLa cells was assayed with alkylated DNA. Double-stranded, covalently closed DNA from phage PM II was treated with methyl methanesulfonate, N-methyl-N-nitrosourea, beta-propiolactone, or diepoxybutane to introduce alkylated bases and alkali-labi...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1976
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430701/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1066672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.8.2629 |
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