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Detection of different types of damage in alkylated DNA by means of human corrective endonuclease (correndonuclease).

Corrective endonuclease (correndunclease) activity of HeLa cells was assayed with alkylated DNA. Double-stranded, covalently closed DNA from phage PM II was treated with methyl methanesulfonate, N-methyl-N-nitrosourea, beta-propiolactone, or diepoxybutane to introduce alkylated bases and alkali-labi...

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Detalhes bibliográficos
Main Authors: Duker, N J, Teebor, G W
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430701/
https://ncbi.nlm.nih.gov/pubmed/1066672
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