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Damage Detection and Base Flipping in Direct DNA Alkylation Repair

To efficiently remove a few damaged bases from the context of the entire genome, the DNA base repair proteins rely on remarkably specific detection mechanisms to locate base lesions. This efficient molecular recognition event inside cells has been extensively studied with various structural and bioc...

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Detalhes bibliográficos
Main Authors: Yang, Cai-Guang, Garcia, Kristel, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777631/
https://ncbi.nlm.nih.gov/pubmed/19145606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800580
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