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KSHV Reactivation and Novel Implications of Protein Isomerization on Lytic Switch Control

In Kaposi’s sarcoma-associated herpesvirus (KSHV) oncogenesis, both latency and reactivation are hypothesized to potentiate tumor growth. The KSHV Rta protein is the lytic switch for reactivation. Rta transactivates essential genes via interactions with cofactors such as the cellular RBP-Jk and Oct-...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Guito, Jonathan, Lukac, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306829/
https://ncbi.nlm.nih.gov/pubmed/25588053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7010072
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