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Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation

Herpesviruses encode numerous microRNAs (miRNAs), most of whose functions are unknown. The Kaposi's sarcoma-associated herpesvirus (KSHV) encodes 17 known miRNAs as part of its latency program, leading to speculation that these RNAs might function, in part, to regulate the latent state. Here we...

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Detalhes bibliográficos
Main Authors: Bellare, Priya, Ganem, Don
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822622/
https://ncbi.nlm.nih.gov/pubmed/20006845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2009.11.008
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