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Effects of NFκB activation on KSHV latency and lytic reactivation are complex and context-dependent
Like all herpesviruses, Kaposi's sarcoma associated herpesvirus (KSHV) can produce either latent or lytic infection. The latent v-FLIP gene is a strong activator of NF-κB, and in primary effusion lymphoma (PEL) cells, blockade of NF-κB activation is associated with enhanced lytic gene expressio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822626/ https://ncbi.nlm.nih.gov/pubmed/18321555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.12.044 |
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