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Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis

Kaposi sarcoma–associated (KS-associated) herpesvirus (KSHV) infection is linked to the development of both KS and several lymphoproliferative diseases. In all cases, the resulting tumor cells predominantly display latent viral infection. KS tumorigenesis requires ongoing lytic viral replication as...

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Detalhes bibliográficos
Main Authors: Grundhoff, Adam, Ganem, Don
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC300762/
https://ncbi.nlm.nih.gov/pubmed/14702116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200417803
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