Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis

Kaposi sarcoma–associated (KS-associated) herpesvirus (KSHV) infection is linked to the development of both KS and several lymphoproliferative diseases. In all cases, the resulting tumor cells predominantly display latent viral infection. KS tumorigenesis requires ongoing lytic viral replication as...

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Pubblicato in:	J Clin Invest
Autori principali:	Grundhoff, Adam, Ganem, Don
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2004
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14702116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI200417803
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