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Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis

Kaposi sarcoma–associated (KS-associated) herpesvirus (KSHV) infection is linked to the development of both KS and several lymphoproliferative diseases. In all cases, the resulting tumor cells predominantly display latent viral infection. KS tumorigenesis requires ongoing lytic viral replication as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grundhoff, Adam, Ganem, Don
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC300762/
https://ncbi.nlm.nih.gov/pubmed/14702116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200417803
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