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Low brain ascorbic acid increases susceptibility to seizures in mouse models of decreased brain ascorbic acid transport and Alzheimer’s disease

Seizures are a known co-occurring symptom of Alzheimer’s disease, and they can accelerate cognitive and neuropathological dysfunction. Sub-optimal vitamin C (ascorbic acid) deficiency, that is low levels that do not lead the sufferer to present with clinical signs of scurvy (e.g. lethargy, hemorrhag...

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Detalhes bibliográficos
Publicado no:Epilepsy Res
Main Authors: Warner, Timothy A, Kang, Jing-Qiong, Kennard, John A, Harrison, Fiona E
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306812/
https://ncbi.nlm.nih.gov/pubmed/25616451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eplepsyres.2014.11.017
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