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Decreased content of ascorbic acid (vitamin C) in the brain of knockout mouse models of Na(+),K(+)-ATPase-related neurologic disorders

Na(+),K(+)-ATPase is a crucial protein responsible for maintaining the electrochemical gradients across the cell membrane. The Na(+),K(+)-ATPase is comprised of catalytic α, β, and γ subunits. In adult brains, the α3 subunit, encoded by ATP1A3, is predominantly expressed in neurons, whereas the α2 s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ikeda, Keiko, Tienda, Adriana A., Harrison, Fiona E., Kawakami, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864419/
https://ncbi.nlm.nih.gov/pubmed/33544780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246678
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