Ablation of AMPKα1 and α2 from pancreatic beta cells and RIP.Cre neurons suppresses insulin release in vivo

AIMS/HYPOTHESIS: AMP-activated protein kinase (AMPK) is an evolutionarily-conserved enzyme and a target of antihyperglycemic agents including metformin. However, the precise role(s) of the enzyme in controlling insulin secretion remains uncertain. METHODS: The catalytic α1 and α2 subunits of AMPK we...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Diabetologia
Main Authors: Sun, G., Tarasov, A.I., McGinty, J., McDonald, A., da Silva Xavier, G., Gorman, T., Marley, A., French, P. M., Parker, H., Gribble, F., Reimann, F., Prendiville, O., Carzaniga, R., Viollet, B., Leclerc, I., Rutter, G.A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306708/
https://ncbi.nlm.nih.gov/pubmed/20221584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-1692-1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker