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Dysregulated intracellular signaling in the striatum in a pathophysiologically grounded model of Tourette syndrome
Tic disorders produce substantial morbidity, but their pathophysiology remains poorly understood. Convergent evidence suggests that dysregulation of the cortico-basal ganglia circuitry is central to the pathogenesis of tics. Tourette syndrome (TS), the most severe end of the continuum of tic disorde...
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| Publicado en: | Eur Neuropsychopharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4306602/ https://ncbi.nlm.nih.gov/pubmed/25464894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2014.10.007 |
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