Topological Models of Heteromeric Protein Assemblies from Mass Spectrometry: Application to the Yeast eIF3:eIF5 Complex

Describing, understanding, and modulating the function of the cell require elucidation of the structures of macromolecular assemblies. Here, we describe an integrative method for modeling heteromeric complexes using as a starting point disassembly pathways determined by native mass spectrometry (MS)...

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Publicado no:Chem Biol
Main Authors: Politis, Argyris, Schmidt, Carla, Tjioe, Elina, Sandercock, Alan M., Lasker, Keren, Gordiyenko, Yuliya, Russel, Daniel, Sali, Andrej, Robinson, Carol V.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306531/
https://ncbi.nlm.nih.gov/pubmed/25544043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.11.010
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