Bortezomib, C1-inhibitor and Plasma Exchange Do Not Prolong the Survival of Multi-transgenic GalT-KO Pig Kidney Xenografts in Baboons

Galactosyl-transferase knock-out (GalT-KO) pigs represent a potential solution to xenograft rejection, particularly in the context of additional genetic modifications. We have performed life supporting kidney xenotransplantation into baboons utilizing GalT-KO pigs transgenic for human CD55/CD59/CD39...

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Gepubliceerd in:Am J Transplant
Hoofdauteurs: Le, Bas-Bernardet S., Tillou, X., Branchereau, J., Dilek, N., Poirier, N., Châtelais, M., Charreau, B., Minault, D., Hervouet, J., Renaudin, K., Crossan, C., Scobie, L., Takeuchi, Y., Diswall, M., Breimer, M.E., Klar, N., Daha, M.R., Simioni, P., Robson, S.C., Nottle, M.B., Salvaris, E.J., Cowan, P.J., d’Apice, A.J.F., Sachs, D.H., Yamada, K., Lagutina, I., Duchi, R., Perota, A., Lazzari, G., Galli, C., Cozzi, E., Soulillou, J.-P., B., Vanhove, Blancho, G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306235/
https://ncbi.nlm.nih.gov/pubmed/25612490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12988
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