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High level of hepatitis B virus DNA after HBeAg-to-anti-HBe seroconversion is related to coexistence of mutations in its precore and basal core promoter

AIM: G1896A mutation in precore or A1762T/G1764A mutations in basal core promoter are suspected to be responsible for patients with detectable level of HBV DNA in serum after seroconversion from HBeAg to anti-HBe. However, G1896A variant has impaired, while A1762T/G1764A variant may have intact repl...

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Publicat a:World J Gastroenterol
Autors principals: Peng, Xiao-Mou, Huang, Gui-Mei, Li, Jian-Guo, Huang, Yang-Su, Mei, Yong-Yu, Gao, Zhi-Liang
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305853/
https://ncbi.nlm.nih.gov/pubmed/15918203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i20.3131
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