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Alpha-fetoprotein triggers hepatoma cells escaping from immune surveillance through altering the expression of Fas/FasL and tumor necrosis factor related apoptosis-inducing ligand and its receptor of lymphocytes and liver cancer cells

AIM: To investigate the mechanism of α-fetoprotein (AFP) in escaping from the host immune surveillance of hepatoc-ellular carcinoma. METHODS: AFP purified from human umbilical blood was administrated into the cultured human lymphoma Jurkat T cell line or hepatoma cell line, Bel7402 in vitro. The exp...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Li, Meng-Sen, Ma, Qiu-Ling, Chen, Qian, Liu, Xin-Hua, Li, Ping-Feng, Du, Guo-Guang, Li, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305744/
https://ncbi.nlm.nih.gov/pubmed/15849812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i17.2564
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