Fas/Fas ligand (FasL)-deregulated apoptosis and IL-6 insensitivity in highly malignant myeloma cells

IL-6 is a growth factor which interferes in the apoptosis of malignant plasma cells. Here we explore its role in the spontaneous and Fas/FasL-regulated apoptosis of seven myeloma cell clones (MCC). MCC-2 and -7 were constitutively defective in Fas antigen in the presence of large membrane exposure o...

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Bibliografiska uppgifter
Huvudupphovsmän: Frassanito, M A, Silvestris, F, Silvestris, N, Cafforio, P, Camarda, G, Iodice, G, Dammacco, F
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 1998
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905107/
https://ncbi.nlm.nih.gov/pubmed/9822274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00711.x
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