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Hypermethylation of CpG island in O(6)-methylguanine-DNA methyltransferase gene was associated with K-ras G to A mutation in colorectal tumor
AIM: To investigate the functions of promoter hypermethylation of O(6)-methylguanine-DNA methyltransferase (MGMT) gene in colorectal tumorigenesis and progression. METHODS: The promoter hypermethylation of MGMT gene was detected in 27 sporadic colorectal adenomas, 62 sporadic colorectal carcinomas a...
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| Publicado no: | World J Gastroenterol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4305730/ https://ncbi.nlm.nih.gov/pubmed/15800999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i13.2022 |
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