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Association between folate levels and CpG island hypermethylation in normal colorectal mucosa

BACKGROUND: Gene-specific promoter methylation of several genes occurs in aging normal tissues and may predispose to tumorigenesis. In the present study, we investigate the association among blood folate levels, and dietary and lifestyle factors with CpG island methylation in normal colorectal mucos...

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Hlavní autoři: Wallace, Kristin, Grau, Maria V., Levine, Joan A., Shen, Lanlan, Hamdan, Randala, Chen, Xinli, Gui, Jiang, Haile, Robert W., Barry, Elizabeth L., Ahnen, Dennis, McKeown-Eyssen, Gail, Baron, John A., Issa, Jean Pierre J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058541/
https://ncbi.nlm.nih.gov/pubmed/21149331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0047
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