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Two miRNA clusters reveal alternative paths in late-stage reprogramming

Ectopic expression of specific factors such as Oct4, Sox2, and Klf4 (OSK) is sufficient to reprogram somatic cells into induced pluripotent stem cells (iPSCs). In this study, we examine the paths taken by cells during the reprogramming process by following the transcriptional activation of two pluri...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Parchem, Ronald J., Ye, Julia, Judson, Robert L., LaRussa, Marie F., Krishnakumar, Raga, Blelloch, Amy, Oldham, Michael C., Blelloch, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305531/
https://ncbi.nlm.nih.gov/pubmed/24630794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.01.021
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