Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells

The embryonic stem cell–specific cell cycle–regulating (ESCC) family of microRNAs (miRNAs) enhances reprogramming of mouse embryonic fibroblasts to induced pluripotent stem cells(1). Here we show that the human ESCC miRNA orthologs hsa-miR-302b and hsa-miR-372 promote human somatic cell reprogrammin...

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Autores principales: Subramanyam, Deepa, Lamouille, Samy, Judson, Robert L, Liu, Jason Y, Bucay, Nathan, Derynck, Rik, Blelloch, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685579/
https://ncbi.nlm.nih.gov/pubmed/21490602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1862
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