Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas

PURPOSE: The genetic differences between Human papilloma Virus (HPV)-positive and negative head and neck squamous cell carcinomas (HNSCC) remain largely unknown. In order to identify differential biology and novel therapeutic targets for both entities we determined mutations and copy number aberrati...

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Publicat a:Clin Cancer Res
Autors principals: Seiwert, Tanguy Y, Zuo, Zhixiang, Keck, Michaela K, Khattri, Arun, Pedamallu, Chandra S., Stricker, Thomas, Brown, Christopher, Pugh, Trevor J., Stojanov, Petar, Cho, Juok, Lawrence, Michael S., Getz, Gad, Brägelmann, Johannes, DeBoer, Rebecca, Weichselbaum, Ralph R, Langerman, Alexander, Portugal, Louis, Blair, Elizabeth, Stenson, Kerstin, Lingen, Mark W., Cohen, Ezra EW, Vokes, Everett E., White, Kevin P., Hammerman, Peter S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305034/
https://ncbi.nlm.nih.gov/pubmed/25056374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3310
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