Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas

PURPOSE: The genetic differences between Human papilloma Virus (HPV)-positive and negative head and neck squamous cell carcinomas (HNSCC) remain largely unknown. In order to identify differential biology and novel therapeutic targets for both entities we determined mutations and copy number aberrati...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Seiwert, Tanguy Y, Zuo, Zhixiang, Keck, Michaela K, Khattri, Arun, Pedamallu, Chandra S., Stricker, Thomas, Brown, Christopher, Pugh, Trevor J., Stojanov, Petar, Cho, Juok, Lawrence, Michael S., Getz, Gad, Brägelmann, Johannes, DeBoer, Rebecca, Weichselbaum, Ralph R, Langerman, Alexander, Portugal, Louis, Blair, Elizabeth, Stenson, Kerstin, Lingen, Mark W., Cohen, Ezra EW, Vokes, Everett E., White, Kevin P., Hammerman, Peter S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305034/
https://ncbi.nlm.nih.gov/pubmed/25056374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3310
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