Developmental control of Polycomb subunit composition by GATA factors mediates a switch to non-canonical functions

Polycomb Repressive Complex 2 (PRC2) plays crucial roles in transcriptional regulation and stem cell development. However, the context-specific functions associated with alternative subunits remain largely unexplored. Here we show that the related enzymatic subunits EZH1 and EZH2 undergo an expressi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell
Main Authors: Xu, Jian, Shao, Zhen, Li, Dan, Xie, Huafeng, Kim, Woojin, Huang, Jialiang, Taylor, Jordan E., Pinello, Luca, Glass, Kimberly, Jaffe, Jacob D., Yuan, Guo-Cheng, Orkin, Stuart H.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305004/
https://ncbi.nlm.nih.gov/pubmed/25578878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.009
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