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B cell activating factor (BAFF) and a proliferation inducing ligand (APRIL) mediate CD40-independent help by memory CD4 T cells

Donor-reactive memory T cells undermine organ transplant survival and are poorly controlled by immunosuppression or costimulatory blockade. Memory CD4 T cells provide CD40-independent help for the generation of donor-reactive effector CD8 T cells and alloantibody that rapidly mediate allograft rejec...

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Bibliografiske detaljer
Udgivet i:Am J Transplant
Main Authors: Gorbacheva, Victoria, Ayasoufi, Katayoun, Fan, Ran, Baldwin, William M., Valujskikh, Anna
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304935/
https://ncbi.nlm.nih.gov/pubmed/25496308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12984
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