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Isolation and partial characterization of a cholesterol-requiring mutant of Chinese hamster ovary cells.

A sterol-requiring mutant has been isolated from mutagenized Chinese hamster ovary cells. This mutant grows normally only when cholesterol is present in the medium. Cell lysis occurs within 3 days in the absence of cholesterol. The frequency of reversion of this mutant to prototrophic growth is low...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Chang, T Y, Telakowski, C, Heuvel, W V, Alberts, A W, Vagelos, P R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430493/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/265577/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.3.832
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