Interrelationships between Ca2+ and adenylate and guanylate cyclases in the control of platelet secretion and aggregation.
Ca2+ is a powerful inhibitor (Ki is congruent to 16 muM) of basal and prostaglandin E1 (PGE1)-stimulated adenylate cyclase [ATP pyrophosphate-lyase (cyclizing); EC 4.6.1.1] activity in membranes obtained from homogenized human platelets. Ca2+ (but not the ionophore A23,187) decreased V(max) of the r...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1976
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6960/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.6.1829 |
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