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Interrelationships between Ca2+ and adenylate and guanylate cyclases in the control of platelet secretion and aggregation.

Ca2+ is a powerful inhibitor (Ki is congruent to 16 muM) of basal and prostaglandin E1 (PGE1)-stimulated adenylate cyclase [ATP pyrophosphate-lyase (cyclizing); EC 4.6.1.1] activity in membranes obtained from homogenized human platelets. Ca2+ (but not the ionophore A23,187) decreased V(max) of the r...

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Bibliografiska uppgifter
Huvudupphovsmän: Rodan, G A, Feinstein, M B
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1976
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC430400/
https://ncbi.nlm.nih.gov/pubmed/6960
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