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Prolonged Fasting Identifies Heat Shock Protein 10 as a Sirtuin 3 Substrate: ELUCIDATING A NEW MECHANISM LINKING MITOCHONDRIAL PROTEIN ACETYLATION TO FATTY ACID OXIDATION ENZYME FOLDING AND FUNCTION
Although Sirtuin 3 (SIRT3), a mitochondrially enriched deacetylase and activator of fat oxidation, is down-regulated in response to high fat feeding, the rate of fatty acid oxidation and mitochondrial protein acetylation are invariably enhanced in this dietary milieu. These paradoxical data implicat...
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| Yayımlandı: | J Biol Chem |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303695/ https://ncbi.nlm.nih.gov/pubmed/25505263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.606228 |
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