Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins

Sirtuins are NAD(+)-dependent lysine deacylases, regulating a variety of cellular processes. The nuclear Sirt1, the cytosolic Sirt2, and the mitochondrial Sirt3 are robust deacetylases, whereas the other sirtuins have preferences for longer acyl chains. Most previous studies investigated sirtuin-cat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Knyphausen, Philipp, de Boor, Susanne, Kuhlmann, Nora, Scislowski, Lukas, Extra, Antje, Baldus, Linda, Schacherl, Magdalena, Baumann, Ulrich, Neundorf, Ines, Lammers, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Enzymology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938187/
https://ncbi.nlm.nih.gov/pubmed/27226597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.726307
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