Restricted mitochondrial protein acetylation initiates mitochondrial autophagy

Because nutrient-sensing nuclear and cytosolic acetylation mediates cellular autophagy, we investigated whether mitochondrial acetylation modulates mitochondrial autophagy (mitophagy). Knockdown of GCN5L1, a component of the mitochondrial acetyltransferase machinery, diminished mitochondrial protein...

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Detalhes bibliográficos
Main Authors: Webster, Bradley R., Scott, Iain, Han, Kim, Li, Jian H., Lu, Zhongping, Stevens, Mark V., Malide, Daniela, Chen, Yong, Samsel, Leigh, Connelly, Patricia S., Daniels, Mathew P., McCoy, J. Philip, Combs, Christian A., Gucek, Marjan, Sack, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074296/
https://ncbi.nlm.nih.gov/pubmed/24006259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.131300
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