Restricted mitochondrial protein acetylation initiates mitochondrial autophagy

Because nutrient-sensing nuclear and cytosolic acetylation mediates cellular autophagy, we investigated whether mitochondrial acetylation modulates mitochondrial autophagy (mitophagy). Knockdown of GCN5L1, a component of the mitochondrial acetyltransferase machinery, diminished mitochondrial protein...

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Main Authors: Webster, Bradley R., Scott, Iain, Han, Kim, Li, Jian H., Lu, Zhongping, Stevens, Mark V., Malide, Daniela, Chen, Yong, Samsel, Leigh, Connelly, Patricia S., Daniels, Mathew P., McCoy, J. Philip, Combs, Christian A., Gucek, Marjan, Sack, Michael N.
格式: Artigo
語言:Inglês
出版: The Company of Biologists 2013
主題:
Short Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074296/
https://ncbi.nlm.nih.gov/pubmed/24006259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.131300
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