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Aip1 Promotes Actin Filament Severing by Cofilin and Regulates Constriction of the Cytokinetic Contractile Ring

Aip1 (actin interacting protein 1) is ubiquitous in eukaryotic organisms, where it cooperates with cofilin to disassemble actin filaments, but neither its mechanism of action nor its biological functions have been clear. We purified both fission yeast and human Aip1 and investigated their biochemica...

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Pubblicato in:J Biol Chem
Autori principali: Chen, Qian, Courtemanche, Naomi, Pollard, Thomas D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303679/
https://ncbi.nlm.nih.gov/pubmed/25451933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612978
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