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Abl2/Abl-related Gene Stabilizes Actin Filaments, Stimulates Actin Branching by Actin-related Protein 2/3 Complex, and Promotes Actin Filament Severing by Cofilin

Both Arp2/3 complex and the Abl2/Arg nonreceptor tyrosine kinase are essential to form and maintain diverse actin-based structures in cells, including cell edge protrusions in fibroblasts and cancer cells and dendritic spines in neurons. The ability of Arg to promote cell edge protrusions in fibrobl...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Courtemanche, Naomi, Gifford, Stacey M., Simpson, Mark A., Pollard, Thomas D., Koleske, Anthony J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326814/
https://ncbi.nlm.nih.gov/pubmed/25540195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608117
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