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Lineage-dependent effects of aryl hydrocarbon receptor agonists contribute to liver tumorigenesis
Rodent cancer bioassays indicate that the aryl hydrocarbon receptor (AHR) agonist, 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD), causes increases in both hepatocytic and cholangiocytic tumors. Effects of AHR activation have been evaluated on rodent hepatic stem cells (rHpSCs) versus their descendants...
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| Publié dans: | Hepatology |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BlackWell Publishing Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303521/ https://ncbi.nlm.nih.gov/pubmed/25284723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27547 |
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