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The many faces of mitophagy

Failure to maintain mitochondrial integrity is linked to age-related conditions, such as neurodegeneration. Two genes linked to Parkinson's disease, PINK1 and Parkin, play a key role in targeting the degradation of dysfunctional mitochondria (mitophagy). However, the mechanisms regulating the P...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Ivatt, Rachael M, Whitworth, Alexander J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303441/
https://ncbi.nlm.nih.gov/pubmed/24398127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338224
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