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The many faces of mitophagy

Failure to maintain mitochondrial integrity is linked to age-related conditions, such as neurodegeneration. Two genes linked to Parkinson's disease, PINK1 and Parkin, play a key role in targeting the degradation of dysfunctional mitochondria (mitophagy). However, the mechanisms regulating the P...

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Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Ivatt, Rachael M, Whitworth, Alexander J
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303441/
https://ncbi.nlm.nih.gov/pubmed/24398127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201338224
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