RNASeq-derived transcriptome comparisons reveal neuromodulatory deficiency in the CO(2) insensitive brown Norway rat

Raphé-derived serotonin (5-HT) and thyrotropin-releasing hormone (TRH) play important roles in fundamental, homeostatic control systems such as breathing and specifically the ventilatory CO(2) chemoreflex. Brown Norway (BN) rats exhibit an inherent and severe ventilatory insensitivity to hypercapnia...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Puissant, Madeleine M, Echert, Ashley E, Yang, Chun, Mouradian, Gary C, Novotny, Tyler, Liu, Pengyuan, Liang, Mingyu, Hodges, Matthew R
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Respiratory
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303386/
https://ncbi.nlm.nih.gov/pubmed/25630262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.285171
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