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RNASeq-derived transcriptome comparisons reveal neuromodulatory deficiency in the CO(2) insensitive brown Norway rat

Raphé-derived serotonin (5-HT) and thyrotropin-releasing hormone (TRH) play important roles in fundamental, homeostatic control systems such as breathing and specifically the ventilatory CO(2) chemoreflex. Brown Norway (BN) rats exhibit an inherent and severe ventilatory insensitivity to hypercapnia...

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Detalles Bibliográficos
Publicado en:J Physiol
Main Authors: Puissant, Madeleine M, Echert, Ashley E, Yang, Chun, Mouradian, Gary C, Novotny, Tyler, Liu, Pengyuan, Liang, Mingyu, Hodges, Matthew R
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303386/
https://ncbi.nlm.nih.gov/pubmed/25630262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.285171
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