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RNASeq-derived transcriptome comparisons reveal neuromodulatory deficiency in the CO(2) insensitive brown Norway rat
Raphé-derived serotonin (5-HT) and thyrotropin-releasing hormone (TRH) play important roles in fundamental, homeostatic control systems such as breathing and specifically the ventilatory CO(2) chemoreflex. Brown Norway (BN) rats exhibit an inherent and severe ventilatory insensitivity to hypercapnia...
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| Veröffentlicht in: | J Physiol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303386/ https://ncbi.nlm.nih.gov/pubmed/25630262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.285171 |
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