Defined Culture of Human Embryonic Stem Cells and Xeno-Free Derivation of Retinal Pigmented Epithelial Cells on a Novel, Synthetic Substrate

Age-related macular degeneration (AMD), a leading cause of blindness, is characterized by the death of the retinal pigmented epithelium (RPE), which is a monolayer posterior to the retina that supports the photoreceptors. Human embryonic stem cells (hESCs) can generate an unlimited source of RPE for...

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Bibliographic Details
Published in:Stem Cells Transl Med
Main Authors: Pennington, Britney O., Clegg, Dennis O., Melkoumian, Zara K., Hikita, Sherry T.
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2015
Subjects:
Protocols and Manufacturing for Cell-Based Therapies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303358/
https://ncbi.nlm.nih.gov/pubmed/25593208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2014-0179
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