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Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo

Age-related macular degeneration (AMD) is the primary cause of blindness in adults over 60 years of age, and clinical trials are currently assessing the therapeutic potential of retinal pigmented epithelial (RPE) cell monolayers on implantable scaffolds to treat this disease. However, challenges rel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pennington, Britney O., Bailey, Jeffrey K., Faynus, Mohamed A., Hinman, Cassidy, Hee, Mitchell N., Ritts, Rory, Nadar, Vignesh, Zhu, Danhong, Mitra, Debbie, Martinez-Camarillo, Juan Carlos, Lin, Tai-Chi, Thomas, Biju B., Hinton, David R., Humayun, Mark S., Lebkowski, Jane, Johnson, Lincoln V., Clegg, Dennis O.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973769/
https://ncbi.nlm.nih.gov/pubmed/33737600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85631-6
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