Xeno-Free and Defined Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells Functionally Integrate in a Large-Eyed Preclinical Model

Human embryonic stem cell (hESC)-derived retinal pigment epithelial (RPE) cells could replace lost tissue in geographic atrophy (GA) but efficacy has yet to be demonstrated in a large-eyed model. Also, production of hESC-RPE has not yet been achieved in a xeno-free and defined manner, which is criti...

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Pubblicato in:Stem Cell Reports
Autori principali: Plaza Reyes, Alvaro, Petrus-Reurer, Sandra, Antonsson, Liselotte, Stenfelt, Sonya, Bartuma, Hammurabi, Panula, Sarita, Mader, Theresa, Douagi, Iyadh, André, Helder, Hovatta, Outi, Lanner, Fredrik, Kvanta, Anders
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720022/
https://ncbi.nlm.nih.gov/pubmed/26724907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.11.008
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