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Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal

[Image: see text] The circulating protein transthyretin (TTR) can unfold, oligomerize, and form highly structured amyloid fibrils that are deposited in tissues, causing organ damage and disease. This pathogenic process is caused by a heritable TTR point mutation in cases of familial TTR-related amyl...

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發表在:Biochemistry
Main Authors: Greene, Michael J., Klimtchuk, Elena S., Seldin, David C., Berk, John L., Connors, Lawreen H.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2014
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303310/
https://ncbi.nlm.nih.gov/pubmed/25478940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5011249
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