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Co-stimulation with TNF receptor superfamily 4/25 antibodies enhances in-vivo expansion of CD4+CD25+Foxp3+ T cells (Tregs) in a mouse study for active DNA Aβ42 immunotherapy

The study was designed to test DNA Aβ42 immunization in mice as alternative approach for possible active immunotherapy in Alzheimer patients. As results, we found polarized Th2 immune responses, efficient Aβ42 antibody levels, and disappearance of antigen specific T cells. In-vivo TNFRSF4/25 antibod...

詳細記述

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書誌詳細
出版年:J Neuroimmunol
主要な著者: Lambracht-Washington, Doris, Rosenberg, Roger N.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303183/
https://ncbi.nlm.nih.gov/pubmed/25595257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2014.12.007
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