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Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis
INTRODUCTION: Transforming growth factor beta (TGFβ) plays a major role in the regulation of tumor initiation, progression, and metastasis. It is depended on the type II TGFβ receptor (TβRII) for signaling. Previously, we have shown that deletion of TβRII in mammary epithelial of MMTV-PyMT mice resu...
שמור ב:
| הוצא לאור ב: | Breast Cancer Res |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4303109/ https://ncbi.nlm.nih.gov/pubmed/25280532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0425-7 |
| תגים: |
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