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Binding of insulin to isolated nuclei.

Specific binding sites for 125I-labeled insulin were detected in purified nuclei isolated from rat liver. Binding was rapid, reversible and directly proportional to the number of nuclei employed. Unlabeled native insulin, at concentrations as low as 1ng/ml, significantly inhibited the binding of lab...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Goldfine, I D, Smith, G J
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1976
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/179086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.5.1427
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