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A Highly Efficient Recombineering-Based Method for Generating Conditional Knockout Mutations

Phage-based Escherichia coli homologous recombination systems have recently been developed that now make it possible to subclone or modify DNA cloned into plasmids, BACs, or PACs without the need for restriction enzymes or DNA ligases. This new form of chromosome engineering, termed recombineering,...

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Détails bibliographiques
Auteurs principaux: Liu, Pentao, Jenkins, Nancy A., Copeland, Neal G.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC430283/
https://ncbi.nlm.nih.gov/pubmed/12618378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.749203
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